Fig. 4

SROC curve with confidence and prediction regions around mean operating sensitivity and specificity point. A SROC curve overall including the outliers for single miR-486; (B) SROC curve of circulating single miR-486; (C) SROC curve of single miR-486 based on large sample size; (D) SROC curve of single miR-486 based on small sample size; (E) SROC curve of outliers excluded for single miR-486; (F) SROC curve of combination biomarkers containing miR-486