Table 4 Statistical Interpretation of Data in Fig. 3A

Controls IP fraction relative to Input Control

Ns change

(P = 0.0814)

1.5-fold higher (P = 0.0098)

1.6-fold lower

(P < 0.0001)

1.5-fold lower

(P = 0.0029)

fivefold lower (P < 0.0001)

2.3-fold higher (P = 0.0005)

2.6-fold lower (P < 0.0001)

1.6-fold lower (P = 0.0036)

1.3-fold lower (P < 0.0001)

BC Patient IP fraction relative to Input Control

1.7-fold higher (P = 0.0417)

Ns Change (P = 0.2682)

twofold lower (P = 0.0253)

Ns Change (P = 0.5620)

sevenfold lower (P = 0.0003)

twofold higher (P = 0.0062)

Ns Change (P = 0.0668)

1.9-fold lower (P = 0.0258)

Ns change (P = 0.2202)

BC Patient IP fraction relative to Controls IP fraction **

1.5-fold higher (P = 0.0212, q = 0.0466)

Ns change (P = 0.5517, q = 0.4809)

Ns change (P = 0.1849, q = 0.2441)

Ns change (P = 0.5829, q = 0.4809)

1.4-fold lower (P = 0.0173, q = 0.0466)

1.2-fold lower (P = 0.012, q = 0.0466)

Ns change (P = 0.1526, q = 0.2441)

Ns change (P = 0.3018, q = 0.332)

Ns change (P = 0.9413, q = 0.6903)