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Fig. 4 | BMC Medical Genomics

Fig. 4

From: LIMA1 inhibits cisplatin resistance and malignant biological behavior of bladder cancer cells by suppressing the Wnt/β-catenin pathway

Fig. 4

LIMA1 overexpression downregulates the Wnt/β-catenin signalling pathway in BCa cells. A. Western blot was used to detect protein expression levels of Wnt3a, β-catenin, and C-myc in J82 cells of siRNA and si-LIMA1 groups, with representative bands provided; B. Results of statistical analysis of Wnt3a, β-catenin, and C-myc protein levels in J82 cells of siRNA and si-LIMA1 groups; C. Western blot was used to detect protein expression levels of Wnt3a, β-catenin, and C-myc in J82/CR cells of vector and LIMA1 groups, with representative bands provided; D. Results of statistical analysis of Wnt3a, β-catenin, and C-myc protein levels in J82/CR cells of vectora and LIMA1 groups. N = 3; **P < 0.01 vs. siRNA group; ##P < 0.01 vs. vector group

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