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Fig. 3 | BMC Medical Genomics

Fig. 3

From: LIMA1 inhibits cisplatin resistance and malignant biological behavior of bladder cancer cells by suppressing the Wnt/β-catenin pathway

Fig. 3

LIMA1 overexpression inhibits the migration and invasion ability of BCa cells. (A) Transwell assay was used to detect the migration ability of J82 cells in siRNA and si-LIMA1 groups; (B) Transwell assay was used to detect the migration ability of J82/CR cells in vector and LIMA1 groups; (C) Transwell assay was used to detect the invasion ability of J82 cells in siRNA and si-LIMA1 groups; (D) Transwell assay was used to detect the invasion ability of J82/CR cells in vector and LIMA1 groups; (E) Western blot assay was used to detect protein expression levels of E-cadherin, N-cadherin, SNail in J82 cells of siRNA and si-LIMA1 groups, and quantitative analysis of the related protein levels was conducted; (F) Western blot assay was used to detect protein expression levels of E-cadherin, N-cadherin, Snail in J82/CR cells of vector and LIMA1 groups, and quantitative analysis of related protein levels was conducted. N = 3; **P < 0.01 vs. siRNA group; ##P < 0.01 vs. vector group

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