Fig. 1

LIMA1 expression is downregulated in BCa tissues and cells. (A) MTT assay was used to detect cell survival of J82 and J82/CR cells treated with different concentration gradients of cisplatin solutions (0, 1, 2, 4, 8, 16 μM), and IC50 was calculated, **P < 0.01; (B) RT-qPCR was used to detect LIMA1 mRNA levels in tumour tissues and adjacent normal tissues, **P < 0.01; (C) RT-qPCR was used to detect LIMA1 mRNA levels in SV-HUC-1, J82 and J82/CR cells; (D) Western blot was used to detect LIMA1 protein levels in SV-HUC-1, J82 and J82/CR cells; N = 3; *P < 0.05 and **P < 0.01 vs. SV-HUC-1 group; #P < 0.05 and ##P < 0.01, vs. J82 group