Fig. 3

Screening of five biomarkers in AMI. (a) Cross-validation for tuning parameter selection in the least absolute shrinkage and selection operator (LASSO) Cox model was shown and five characteristic genes were selected. (b) Receiver operating characteristic (ROC) curves of the LASSO model-based genes in the support vector machine recursive feature elimination (SVM-RFE) and the extreme gradient boosting (XGBoost) algorithms. (c) ROC analysis of five characteristic genes in the GSE60993 and GSE48060 datasets. (d) Boxplots for the expression levels of five characteristic genes in the GSE60993 and GSE48060 datasets. (e) Results of quantitative PCR (qPCR) for the expression levels of five characteristic genes in the clinical AMI and normal blood samples. * P < 0.05, ** P < 0.01, *** P < 0.001