Fig. 2
From: MEIS1 knockdown upregulates WNT signaling pathway genes in esophageal squamous cell carcinoma
Lentiviral transduction enforced remarkable MEIS1 underexpression in KYSE-30 nearly − 4 folds compared to control. MEIS1 knockdown up-regulates the main components of WNT signaling pathway including DVL1, LRP5, LEF1/TCF7 and FZD1 expression and down regulates the expression of negative regulators of the pathway including APC/GSK3β and FBXW in KYSE-30 cells. The results are assessed using ΔΔct method and presented as log2 fold change ± SD