Skip to main content
Fig. 1 | BMC Medical Genomics

Fig. 1

From: Causal association between non-steroidal anti-inflammatory drugs use and the risk of benign prostatic hyperplasia: a univariable and multivariable Mendelian randomization study

Fig. 1

The study design overview for analyzing the causal effects of NSAIDs use on the risk of BPH using Mendelian randomization. Assumption 1: instrumental variables (IVs) exhibit robust associations with the exposures; Assumption 2: IVs are not associated with any potential confounding factors; Assumption 3: genetic instruments exert their sole impact on the outcome through the relevant exposures. SNP: single nucleotide polymorphisms, NSAIDs: non-steroidal anti-inflammatory drugs, LD: linkage disequilibrium, MR: Mendelian randomization, IVW: inverse variance weighted

Back to article page

BMC Medical Genomics

ISSN: 1755-8794

Contact us