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Fig. 6 | BMC Medical Genomics

Fig. 6

From: Methylation patterns of the nasal epigenome of hospitalized SARS-CoV-2 positive patients reveal insights into molecular mechanisms of COVID-19

Fig. 6

Differential regulation of immune cells and the response, as well as differential response to foreign pathogens are present in severe vs mild COVID-19. Utilizing the overlapping genes identified in our original dataset and the datasets of Gómez-Carballa et al. [62] and Rombauts et al. [63], the top 25 most significantly enriched GO Biological Processes, KEGG Pathways, and Reactome Gene Sets are displayed from relatively (A) hypo- and (B) hypermethylated in severe vs mild COVID-19. Ontologies are listed along the y-axis. -Log P values are displayed along the x-axis

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