Fig. 5

Hypermethylation of the ELF5 promoter in nasopharyngeal samples of COVID-19 positive as compared to COVID-19 negative individuals. WGBS methylation analysis demonstrating hypermethylation of the ELF5 promoter (yellow rectangle) in individuals with severe COVID-19 (top panel) and mild COVID-19 (middle panel) as compared to negative controls (bottom panel). Y-axis demonstrates percent methylation at a given CpG site (0–100%). Figure generated using the UCSC Genome Browser