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Fig. 2 | BMC Medical Genomics

Fig. 2

From: Methylation patterns of the nasal epigenome of hospitalized SARS-CoV-2 positive patients reveal insights into molecular mechanisms of COVID-19

Fig. 2

Distribution of hypomethylated and hypermethylated differentially methylated regions (DMRs) by chromosome in severe versus mild COVID-19 and GO Biological Processes, KEGG Pathways, and Reactome Gene Sets associated with differentially methylated genes (DMGs) in severe versus mild COVID-19. A The top 10,000 DMRs according to q-value were subdivided by chromosomal location (y-axis). The percentage (x-axis) of relatively hypermethylated (blue) and hypomethylated (orange) DMRs in severe as compared to mild COVID-19 cases is shown on a per chromosome basis. B-C The most significant (p < 1 × 10–3) GO Biological Processes, KEGG Pathways, and Reactome Gene Sets related to the immune response in relatively hypomethylated (B) and hypermethylated (C) DMGs in individuals with severe as compared to mild COVID-19. -Log P values are displayed along the x-axis

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BMC Medical Genomics

ISSN: 1755-8794

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