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Table 3 Associations between previously reported SNPs and lifetime meth use in CNICS

From: A genome-wide association study of methamphetamine use among people with HIV

Publication

Total Sample Size

Rs

Gene

Chr

Position

EA

NEA

EAF

Observed OR

Reported p-value

Observed p-value

Ikeda et al. [12]

1,100

rs4427170

SGCZ

8

14996272

T

A

0.28 (Meta)

0.41 (EUR)

0.45 (AMR)

0.15 (AFR)

1.05

3.9e-6

0.41 (Meta)

0.44 (EUR)

0.95 (AMR)

0.59 (AFR)

Chang et al. [11]

4,608

rs112706556

ANKS1B

12

99494606

A

G

0.19 (Meta)

0.17 (EUR)

0.18 (AMR)

0.21 (AFR)

0.96

1.5e-8

0.52 (Meta)

0.82 (AMR)

0.24 (EUR)

0.59 (AFR)

  1. Reported p-value corresponds to the value reported in the original manuscript. Observed p-value corresponds to the p-value for that SNP found in our analysis. ‘Meta’ corresponds to the EAF and p-value found in the overall meta-analysis. EA Effect Allele, NEA Non-Effect Allele, OR Odds Ratio, EUR European Ancestry, AMR Admixed American Ancestry, AFR African Ancestry