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Table 1 Study participants by meth use status and ancestry

From: A genome-wide association study of methamphetamine use among people with HIV

 

Never Used Meth (n, %)

Ever Used Meth (n, %)

Total

p-value

Sex

 Male

3606 (75.9%)

1103 (92.2%)

4709 (79.2%)

 < 0.001

 Female

1144 (24.1%)

93 (7.8%)

1237 (20.8%)

Age at Visit (mean ± SD)

39.7 ± 10.7

38.1 ± 9.3

39.5 ± 10.3

 < 0.001

Ancestry

 AFR

2845 (59.9%)

237 (19.8%)

3082 (51.8%)

0.15

 AMR

690 (14.5%)

307 (25.7%)

997 (16.8%)

0.15

 EUR

1215 (25.6%)

652 (54.5%)

1867 (31.4%)

0.15

Array

 Illumina Infinium MEG

1398 (29.4%)

235 (19.6%)

1633 (27.5%)

 

 Illumina MEGA

1484 (31.2%)

484 (40.4%)

1968 (33.1%)

 

 Illumina MEGA-Ex

1868 (39.3%)

477 (39.9%)

2345 (39.4%)

 

Site

 CWRU

511 (10.8%)

21 (1.8%)

532 (8.9%)

 

 FENW

264 (5.6%)

162 (13.5%)

424 (7.1%)

 

 JH

880 (18.5%)

39 (3.3%)

919 (15.5%)

 

 UAB

1571 (33.1%)

161 (13.5%)

1732 (29.1%)

 

 UCSD

628 (13.2%)

340 (28.4%)

968 (16.3%)

 

 UCSF

82 (1.7%)

179 (15.0%)

261 (4.4%)

 

 UNC

529 (11.1%)

43 (3.6%)

572 (9.6%)

 

 UW

285 (6.0%)

251 (21.0%)

536 (9.0%)

 

Dropout Rate

 

13.0%

15.0%a

15.0%

 

Total

4750 (79.9%)

1196 (20.1%)

5946 (100%)

 
  1. Never Used/Ever Used refer to lifetime methamphetamine use. SD Standard Deviation, AFR African Ancestry, AMR Admixed American Ancestry, EUR European Ancestry, MEG Multi-Ethnic Global-8 Kit, MEGA Multi-ethnic Global Array, MEGAEx Multi-ethnic Global Array Expanded Version. Sites: CWRU Case Western Reserve University, Cleveland, OH, FENW Fenway Health Centers, Boston, MA, JHU Johns Hopkins University, Baltimore, MA, UAB University of Alabama, Birmingham, AL, UCSD University of California San Diego, La Jolla, CA, UCSF University of California San Francisco, San Francisco, CA, UNC University of North Carolina, Chapel Hill, NC, UW University of Washington, Seattle, WA
  2. aDropout rate among individuals who reported ever having used meth was 15%. However, the same rate among individuals who reported using meth at their most recent visit was 19%