Fig. 3

Infiltration of immune cells of the IS and control groups. (A) Bar plot showing percentages of 25 immune cells of the IS and control groups. (B) Correlation between 25 immune cells. (C) Comparison of 25 immune cell subtypes between the IS and control groups. (D–H) Correlations of immune cells with Jun, Myc, Nfe2l2, Rela, and Stat3. Dots of a larger size represent greater p-values. (I–M) Correlation analysis between the five hub DEFRGs (Jun, Myc, Nfe2l2, Rela, and Stat3) and chemokines, immune inhibitors, immune stimulators, MHC, and receptors. *p < 0.05; **p < 0.01; ***p < 0.001; N.S., nonsignificant