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Table 2 The gene detection analysis during treatment

From: Comprehensive clinical and genetic characterization of hyperprogressive biliary tract cancer during PD-1 blockade monotherapy: case report and literature review

Time

Gene

2018.06.01

(baseline)

2019.01.14

(HPD)

Plasma

Tumor Tissue

Plasma

Tumor Tissue

CDKN2A

PIK3CA

EPHA2

KRAS

missense mutation

missense mutation

frameshift mutation

missense mutation

7.96%

7.87%

6.57%

4.90%

2.36%

3.90%

3.73

-

5.16%

4.98%

5.89%

7.97

-

21.93%

18.24%

35.39%