Table 2 Hardy–Weinberg genetic balance test
From: Relationship between mucin gene polymorphisms and different types of gallbladder stones
SNP | Genotypes | MAF | Control | HWE | Stone | HWE |
|---|---|---|---|---|---|---|
MUC1 | ||||||
rs4072037 | C/C | 0.20 | 4(3.74%) | 0.58 | 2(1.65%) | 0.52 |
T/C | 40(37.38%) | 38(31.41%) | ||||
T/T | 63(58.88%) | 81(66.94%) | ||||
MUC2 | ||||||
rs41349846 | A/A | 0.35 | 8(7.48%) | 0.13 | 19(15.70%) | 0.44 |
G/A | 55(51.40%) | 52(42.98%) | ||||
G/G | 44(41.12%) | 50(41.32%) | ||||
rs41532344 | T/T | 0.10 | 0(0.00%) | 1.00 | 1(0.83%) | 1.00 |
C/T | 17(15.89%) | 26(21.49%) | ||||
C/C | 90(84.11%) | 94(77.68%) | ||||
rs2856111 | C/C | 0.49 | 31(28.97%) | 0.56 | 22(18.18%) | 0.27 |
T/C | 50(46.73%) | 67(55.37%) | ||||
T/T | 26(24.30%) | 32(26.45%) | ||||
MUC4 | ||||||
rs712005 | G/G | 0.22 | 5(4.67%) | 0.33 | 12(9.92%) | 0.10 |
A/G | 29(27.10%) | 39(32.23%) | ||||
A/A | 73(68.22%) | 70(57.85%) | ||||
rs2246980 | C/C | 0.28 | 7(6.54%) | 1.00 | 11(9.09%) | 0.83 |
G/C | 43(40.19%) | 49(40.50%) | ||||
G/G | 57(53.27%) | 61(50.41%) | ||||
rs2258447 | T/T | 0.21 | 2(1.87%) | 0.73 | 7(5.78%) | 0.81 |
C/T | 33(30.84%) | 43(35.54%) | ||||
C/C | 72(67.29%) | 71(58.68%) | ||||
rs2259292 | C/C | 0.28 | 6(5.61%) | 0.80 | 13(10.74%) | 0.52 |
T/C | 43(40.19%) | 48(39.67%) | ||||
T/T | 58(54.21%) | 60(49.59%) | ||||
MUC5AC | ||||||
rs28415193 | G/G | 0.27 | 6(5.66%) | 0.57 | 14(11.57%) | 0.40 |
C/G | 34(32.08%) | 48(39.67%) | ||||
C/C | 66(62.26%) | 59(48.76%) | ||||
rs56047977 | A/A | 0.20 | 5(4.67%) | 0.53 | 3(2.48%) | 0.40 |
G/A | 31(28.97%) | 42(34.71%) | ||||
G/G | 71(66.36%) | 76(62.81%) | ||||
MUC5B | ||||||
rs2037089 | C/C | 0.06 | 0(0.00%) | 1.00 | 0(0.00%) | 1.00 |
T/C | 12(11.21%) | 16(13.22%) | ||||
T/T | 95(88.79%) | 105(86.78%) | ||||
rs2075854 | A/A | 0.48 | 23(21.50%) | 0.70 | 28(23.14%) | 0.86 |
G/A | 56(52.34%) | 62(51.24%) | ||||
G/G | 28(26.17%) | 31(25.62%) | ||||
rs3829224 | A/A | 0.28 | 6(5.61%) | 0.62 | 9(7.44%) | 0.83 |
G/A | 45(42.06%) | 51(42.15%) | ||||
G/G | 56(52.34%) | 61(50.41%) | ||||
rs2672785 | G/G | 0.41 | 17(15.89%) | 0.41 | 24(19.83%) | 1.00 |
A/G | 46(42.99%) | 59(48.76%) | ||||
A/A | 44(41.12%) | 38(31.41%) | ||||
rs2735709 | G/G | 0.34 | 13(12.15%) | 0.83 | 9(7.44%) | 0.10 |
C/G | 51(47.66%) | 62(51.24%) | ||||
C/C | 43(40.19%) | 50(41.32%) | ||||
MUC6 | ||||||
rs10902268 | A/A | 0.17 | 1(0.93%) | 0.30 | 6(4.96%) | 0.09 |
G/A | 34(31.78%) | 28(23.14%) | ||||
G/G | 72(67.29%) | 87(71.90%) | ||||
rs573849895 | T/T | 0 | 0(0.00%) | 1.00 | 0(0.00%) | 1.00 |
G/T | 0(0.00%) | 0(0.00%) | ||||
G/G | 107(100.00%) | 121(100.00%) | ||||
rs59257210 | T/T | 0.28 | 9(8.41%) | 0.62 | 8(6.61%) | 0.65 |
C/T | 40(37.38%) | 52(42.98%) | ||||
C/C | 58(54.21%) | 61(50.41%) | ||||
rs61869016 | C/C | 0.38 | 14(13.08%) | 1.00 | 22(18.18%) | 0.12 |
T/C | 50(46.73%) | 49(40.50%) | ||||
T/T | 43(40.19%) | 50(41.32%) | ||||
rs7396383 | T/T | 0.42 | 18(16.82%) | 0.69 | 20(16.53%) | 0.36 |
A/T | 49(45.79%) | 65(53.72%) | ||||
A/A | 40(37.38%) | 36(29.75%) | ||||
rs74644072 | T/T | 0.31 | 15(14.02%) | 0.28 | 11(9.09%) | 0.50 |
C/T | 43(40.19%) | 46(38.02%) | ||||
C/C | 49(45.79%) | 64(52.89%) | ||||
rs7481521 | T/T | 0.27 | 5(4.67%) | 0.32 | 10(8.26%) | 1.00 |
C/T | 46(42.99%) | 49(40.50%) | ||||
C/C | 56(52.34%) | 62(51.24%) | ||||
rs9704308 | C/C | 0.14 | 2(1.87%) | 0.67 | 3(2.48%) | 1.00 |
T/C | 23(21.50%) | 31(25.62%) | ||||
T/T | 82(76.64%) | 87(71.90%) | ||||
MUC17 | ||||||
rs10229731 | C/C | 0.23 | 4(3.74%) | 0.42 | 9(7.44%) | 0.20 |
A/C | 42(39.25%) | 38(31.40%) | ||||
A/A | 61(57.01%) | 74(61.16%) | ||||
rs4729655 | T/T | 0.32 | 12(11.21%) | 0.50 | 17(14.05%) | 0.16 |
C/T | 43(40.19%) | 47(38.84%) | ||||
C/C | 52(48.60%) | 57(47.11%) | ||||
rs55903219 | C/C | 0.45 | 24(22.43%) | 0.56 | 29(23.97%) | 0.06 |
T/C | 50(46.73%) | 49(40.50%) | ||||
T/T | 33(30.84%) | 43(35.53%) | ||||
rs73168398 | A/A | 0.13 | 3(2.80%) | 0.46 | 2(1.65%) | 0.64 |
G/A | 25(23.36%) | 23(19.01%) | ||||
G/G | 79(73.83%) | 96(79.34%) | ||||
rs74974199 | C/C | 0.11 | 2(1.87%) | 0.63 | 1(0.83%) | 1.00 |
G/C | 21(19.63%) | 21(17.35%) | ||||
G/G | 84(78.50%) | 99(81.82%) | ||||