Fig. 5

The KIRC-associated diagnosis model and eRNA-centric regulatory network. A Pattern diagram for model establishment; B The volcano plot of DE eRNAs significantly associated with tumorigenesis; C ROC curves of diagnosis eRNA factors (lambda. min = 29, lambda.1se = 4); D The TF-eRNA-EP loop regulatory network centered on up-regulated RNA, which only includes KIRC-annotated DEGs; E The barplot of the average number of edges of eRNA and overall in this network; F The most densely connected module from this up-regulated eRNA-centric regulatory network; G The barplot of GO enrichment analysis results of up-regulated eRNA-centric regulatory network; H The TF-eRNA-EP loop regulatory network centered on down-regulated RNA, which only include KIRC-annotated DEGs; I The barplot of the average number of edges of eRNA and overall in this network; J The most densely connected module from the this down-regulated eRNA-centric regulatory network; K The barplot of GO enrichment analysis results of down-regulated eRNA-centric regulatory network;