Table 2 The association between miRNAs expressions and clinical-pathological characteristics of CRC patients

Tissue type

Colon

0.76 ± 1.29

0.35 (0.14–0.57)

0.00012 ± 0.00012

0.00007 (0.00003-0.00019)

Rectum

0.62 ± 0.92

0.36 (0.14–0.68)

0.00014 ± 0.00010

0.00013 (0.00008-0.00019)

p-value

0.775

0.185

Gender

Female

1.13 ± 1.65

0.36 (0.14–1.62)

0.00012 ± 0.00012

0.00009 (0.00004-0.00017)

Male

0.46 ± 0.66

0.34 (0.14–0.49)

0.00013 ± 0.00011

0.00010 (0.00004-0.00019)

p-value

0.275

0.726

Age

≥ 55

0.73 ± 1.18

0.33 (0.15–0.68)

0.00012 ± 0.00011

0.00009 (0.00004-0.00017)

< 55

0.68 ± 1.23

0.41(0.09–0.49)

0.00014 ± 0.00012

0.00010 (0.00004-0.00019)

p-value

0.983

0.444

Neural invasion

Positive

0.89 ± 1.33

0.48 (0.21–0.75)

0.00011 ± 0.00011

0.00008 (0.00003-0.00018)

Negative

0.67 ± 1.15

0.31 (0.14–0.57)

0.00013 ± 0.00012

0.00010 (0.00004-0.00019)

p-value

0.248

0.455

Lymphovascular invasion

Positive

0.77 ± 1.19

0.41 (0.14–0.68)

0.00011 ± 0.00010

0.00008 (0.00003-0.00017)

Negative

0.70 ± 1.20

0.34 (0.15–0.57)

0.00014 ± 0.00012

0.00010 (0.00004-0.00019)

p-value

0.690

0.264

Stage

I-II

0.88 ± 1.38

0.40 (0.15–0.90)

0.00015 ± 0.00012

0.00011 (0.00005–0.00020)

III-IV

0.56 ± 0.96

0.26 (0.12–0.49)

0.00011 ± 0.00011

0.00007 (0.00003-0.00015)

p-value

0.120

0.104

Tumor histology

Adenocarcinoma

0.76 ± 1.31

0.34 (0.14–0.49)

0.00014 ± 0.00012

0.00010 (0.00004–0.00020)

Mucinous adenocarcinoma

0.57 ± 0.56

0.47 (0.26–0.75)

0.00011 ± 0.00008

0.00010 (0.00004-0.00014)

p-value

0.357

0.644