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Table 2 Patient characteristics at admission

From: Blood from septic patients with necrotising soft tissue infection treated with hyperbaric oxygen reveal different gene expression patterns compared to standard treatment

 

HBOx1 group (N = 69)

HBOx2 group

(N = 14)

non-HBO group

(N = 10)

Age

61 (54 – 68)

55 (51 – 70)

58 (53 – 64)

Sex, male

48 (70)

7 (50)

7 (70)

BMI (kg/m2)

26 (23 – 31)

26 (23 −31)

25 (23 – 37)

Comorbidities

 Cardiovascular disease

38 (55)

5 (36)

7 (70)

 Chronic kidney injury

5 (7)

1 (7)

2 (20)

 COPD

7 (10)

1 (7)

1 (10)

 Diabetes (type 1 and 2)

25 (36)

4 (28)

4 (40)

 Immune deficiently

3 (4)

0

2 (20)

 Chronic liver disease

1 (1.4)

1 (7)

2 (20)

 Malignancy

3 (4)

2 (14)

0

 Peripheral vascular disease

8 (11)

2 (14)

1 (10)

 Rheumatoid disease

2 (3)

1 (7)

1 (10)

 No comorbidities

16 (23)

4 (29)

3 (30)

Microbial findings

 Monomicrobial

29 (42)

2 (14.3)

3 (30)

 Polymicrobial

32 (46)

9 (64.3)

7 (70)

 Negative

8 (12)

3 (21.4)

0

Body-part affected

 Head/neck

14 (20)

3 (21.5)

1 (10)

 Abdomen/genitals

32 (46)

9 (64.5)

2 (20)

 Upper extremity

8 (12)

1 (7)

4 (40)

 Lower extremity

15 (22)

1 (7)

3 (30)

Paraclinical parameters

 White blood cell count (× 109 /L)

15 (11–22)

22 (14–30)

12 (8–17)

 Platelet count (× 109 /L)

195 (127 – 317)

206 (196 – 316)

120 (96–218)

 eGFR (ml.min.per.1.73 m)

64 (36 – 90)

47 (21 – 79)

28 (23 – 42)

 Creatinine (µmol/l)

95 (64 – 152)

96 (82 – 231)

192 (156 – 243)

 CRP (mg/L)

233 (138 – 316)

246 (200 – 296)

330 (163–392)

 Lactate dehydrogenase (U/L)

186 (154 – 240)

148 (136 – 183)

238 (199 – 322)

  1. Continuous data are presented as median (interquartile range, IQR) and categorical data as absolute numbers (%). HBO2 = hyperbaric oxygen treatment, COPD = chronic obstructive pulmonary disease. eGFR = estimated glomerular filtration rate. CRP = C Reactive Protein. For lymphocytes and creatinine eight measurements were missing, for eGFR 10 measurement were missing, for thrombocytes 12 measurements were missing, for CRP 15 measurements were missing and for lactate dehydrogenase 52 measurements were missing