Table 5 Results of ablation experiments on the Kiba dataset
From: Drug-target binding affinity prediction based on power graph and word2vec
Model | Protein encoding | Compound rep | MSE | CI |
|---|---|---|---|---|
Remove word2vec | One-hot | (A, A2, A3) | 0.216 | 0.867 |
Remove (A, A2) | Word2vec | A3 | 0.143 | 0.886 |
Remove (A, A3) | Word2vec | A2 | 0.145 | 0.889 |
Remove (A2, A3) | Word2vec | A | 0.137 | 0.895 |
WPGraphDTA | Word2vec | (A, A2, A3) | 0.134 | 0.898 |