The association between vitamin D receptor gene polymorphism FokI and type 2 diabetic kidney disease and its molecular mechanism: a case control study

Table 4 FokI genotype distribution in low-medium group and high risk group for T2DKD progression under different genetic models

		Homozygotes		Invisible model		Dominant model
		OR(95%CI)	P value	OR(95%CI)	P value	OR(95%CI)	P value
Low-to-medium risk group vs. high-risk group	Model 1	0.903(0.356–2.289)	0.829	0.743(0.346–1.598)	0.448	1.184(0.566–2.474)	0.654
Low-to-medium risk group vs. high-risk group	Model 2	2.068(0.537–7.968)	0.291	1.256(0.505–3.120)	0.624	1.413 (0.574–3.479)	0.452

Model 1: Univariate logistic regression analysis
Model2: Adjusted for diabetes course, hypertension history, HBA1c, TC, TG, LDL-C, HDL-C, serum uric acid, NLR, and serum albumin
Homozygotes: T/T vs. C/C (ff vs. FF); Invisible model; T/T vs. C/C + C/T (ff vs. FF + Ff): Dominant model; C/T + T/T vs. C/C (Ff + ff vs. FF)

ISSN: 1755-8794