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Table 2 Table 2 presents the sex-wise mean 5mC modification estimates at single CpG positions within the DMR (chr15:23647640–23647939) in the HFA group. These results were derived from differential methylation analysis at single loci using DSS callDML function, which the callDMR function is based on

From: Sex differences in MAGEL2 gene promoter methylation in high functioning autism - trends from a pilot study using nanopore Cas9 targeted long read sequencing

CpG (chr15:)

Relation to TSS

(chr15:23647867)

Mean Methylation

HFA group

diff

SE (diff)

stat

pval

  

male

female

    

23647640

−227

0.404

0.459

0.055

0.012

4.494

< 0.001

23647644

−223

0.403

0.458

0.056

0.012

4.677

< 0.001

23647651

−216

0.404

0.458

0.055

0.012

4.642

< 0.001

23647662

−205

0.404

0.458

0.055

0.012

4.752

< 0.001

23647669

−198

0.404

0.458

0.055

0.012

4.752

< 0.001

23647683

−184

0.401

0.454

0.054

0.011

4.682

< 0.001

23647689

−178

0.398

0.450

0.053

0.011

4.749

< 0.001

23647698

−169

0.395

0.447

0.053

0.011

4.800

< 0.001

23647701

−166

0.394

0.447

0.052

0.011

4.842

< 0.001

23647710

−157

0.394

0.447

0.052

0.011

4.842

< 0.001

23647737

−130

0.399

0.450

0.051

0.010

5.209

< 0.001

23647776

−91

0.400

0.451

0.051

0.010

5.280

< 0.001

23647821

−46

0.400

0.451

0.051

0.010

5.014

< 0.001

23647878

+ 11

0.399

0.451

0.052

0.011

4.791

< 0.001

23647883

+ 16

0.399

0.451

0.052

0.011

4.705

< 0.001

23647893

+ 26

0.398

0.451

0.052

0.011

4.617

< 0.001

23647928

+ 61

0.397

0.450

0.053

0.010

5.126

< 0.001

23647939

+ 72

0.396

0.448

0.051

0.012

4.464

< 0.001