Fig. 1

The location of G1958A (rs2236225) polymorphism in MTHFD1 gene (SNP2). The genetic variation is named according to the DNA sequence of the human MTHFD1 gene (Genbank database: NG_011992). The transcription start site is located at 1350 in the promoter. Figure 1 is drawn by Illustrator for Biological Sequences (IBS 2.0). Abbreviations: transcriptional start sites (TSS); coding DNA sequences (CDS); single nucleotide polymorphism (SNP)