Table 3 Sensitivity and specificity of CMg compared to qPCR and routine microbiology testing
From: Development of a clinical metagenomics workflow for the diagnosis of wound infections
Target species | Sensitivity (%) | Specificity (%) | ||||
|---|---|---|---|---|---|---|
≥ 5 reads | ≥ 50 reads | 0.1% classified microbial reads | ≥ 5 reads | ≥ 50 reads | 0.1% classified microbial reads | |
E. coli | 62.50 | 37.50 | 50.00 | 78.13 | 87.50 | 84.38 |
P. aeruginosa | 77.78 | 66.67 | 77.78 | 87.10 | 96.77 | 96.77 |
S. aureus | 95.00 | 80.00 | 80.00 | 50.00 | 100.00 | 80.00 |
S. pyogenes | 100.00 | 100.00 | 100.00 | 51.35 | 78.38 | 70.27 |