Table 4 Top 5 GO terms related to biological processes (BP) from the eight comparisons, including the number of genes associated with each gene, and their ranks from the original and bootstrap based GSEA

GSE207890

Smn1δSKM + AFS

vs Ctrl

Skeletal muscle

GO:0001667

Ameboidal-type cell migration

463

4.4*10^–7

2 (1)

GO:0034329

Cell junction assembly

477

4.4*10^–7

2 (2)

GO:0045765

Regulation of angiogenesis

469

2.0*10^–6

2 (4)

GO:0007015

Actin filament organization

489

1.4*10^–6

4 (5)

GO:0060537

Muscle tissue development

300

1.9*10^–6

5 (3)

GSE207890 Smn1δSKM vs Ctrl

Skeletal muscle

GO:0046631

alpha–beta T cell activation

216

2.6*10^–6

1 (1)

GO:0032943

Mononuclear cell proliferation

463

2.9*10^–6

2 (4)

GO:0052548

Regulation of endopeptidase activity

324

2.8*10^–6

3 (3)

GO:0007159

Leukocyte cell–cell adhesion

300

2.8*10^–6

4 (5)

GO:0001667

ameboidal-type cell migration

370

2.8*10^–6

5 (6)

GSE10224

SMA vs Ctrl

Motor neurons

GO:0055002

Striated muscle cell development

63

2.0*10^–8

2 (1)

GO:0030239

Myofibril assembly

62

2.0*10^–8

2 (2)

GO:0031032

Actomyosin structure organization

175

2.0*10^–8

2 (3)

GO:0010927

Cellular component assembly involved in morphogenesis

105

2.0*10^–8

4 (4)

GO:0055001

Muscle cell development

193

2.0*10^–8

5 (5)

GSE10224 transSMA vs Ctrl Motor neurons

GO:0030198

Extracellular matrix organization

258

7.8*10^–9

2 (2)

GO:0043062

Extracellular structure organization

259

7.8*10^–9

2 (1)

GO:0045229

External encapsulating structure organization

259

7.8*10^–9

2 (3)

GO:0010810

Regulation of cell-substrate adhesion

199

7.8*10^–9

4 (4)

GO:0031589

cell-substrate adhesion

195

7.8*10^–9

5 (7)

E-MEXP-2428 Spinal cord

GO:0030198

Extracellular matrix organization

272

1.4*10^–7

2 (1)

GO:0043062

Extracellular structure organization

273

1.4*10^–7

2 (2)

GO:0045229

External encapsulating structure organization

273

1.4*10^–7

2 (3)

GO:0007272

Ensheathment of neurons

148

1.4*10^–7

4 (4)

GO:0001525

Angiogenesis

473

1.4*10^–7

5 (6)

GSE154106

Brain

GO:0071230

Cellular response to amino acid stimulus

154

7.8*10^–8

3 (1)

GO:0043200

Response to amino acid

169

7.8*10^–8

3 (2)

GO:0071229

Cellular response to acid chemical

167

7.8*10^–8

3 (3)

GO:0001101

Response to acid chemical

188

7.8*10^–8

3 (4)

GO:0060291

Long-term synaptic potentiation

236

7.8*10^–8

3 (5)

GSE102204

Brain

GO:0000070

Mitotic sister chromatid segregation

165

0.42

1 (3)

GO:0000819

Sister chromatid segregation

203

0.25

2 (2)

GO:0007059

Chromosome segregation

359

0.19

3 (1)

GO:0098813

Nuclear chromosome segregation

73

0.67

4 (5)

GO:0051304

Chromosome separation

116

0.42

5 (7)

GSE56284 Embryonic stem cell-derived motor neurons

GO:1,903,487

Regulation of lactation

21

1.5*10^–8

2.5 (1)

GO:1,903,489

Positive regulation of lactation

20

1.5*10^–8

2.5 (3)

GO:0007416

Synapse assembly

228

1.5*10^–8

2.5 (2)

GO:0007595

Lactation

81

1.5*10^–8

2.5 (6)

GO:0030534

Adult behavior

52

1.5*10^–8

5.0 (4)