Table 1 Detailed information on the six selected studies including their GEO or Array Express accession ID and their corresponding Pubmed references
GEO or AE ID | Sequencing or microarray platform | Study type* MA/RNAseq | Per group sample sizes (control, diseased) | Tissue | Mouse model | References |
|---|---|---|---|---|---|---|
GSE207890 | Agilent-028005 SurePrint G3 Mouse GE 8 × 60K | MA | 8 Control, 12 Smn1deltaSKM, 7 Smn1deltaSKM + AFS | Skeletal muscle | Smn1 knockout 3 months-old, Smn1 knockout treated with amniotic fluid stem | [10] |
GSE154106 | Illumina HiSeq 2500 | RNA Seq | 4, 4 | Brain | Severe Taiwanese SMA mouse model | [31] |
GSE102204 | Illumina HiSeq 2000 | RNA Seq | 10, 10 | Brain | Early-symptomatic and late-symptomatic | [3] |
GSE56284 | Illumina HiSeq 2500 | RNA Seq | 3, 3 | Embryonic stem cell-derived motor neurons | Mouse embryonic stem cell model | [37] |
GSE10224 | Affymetrix Mouse Expression 430A Array | MA | 3 (Control), 3 (SMA), 3 (Transplanted SMA) | Motor neurons of the spinal cord | Transgenic SMA and transplanted mice | [13] |
E-MEXP-2428 | Affymetrix GeneChip Mouse Exon 1.0 ST Array | MA | 8 (normal), 7 (SMA) | Whole spinal cord | Severe mice model | [41] |