Fig. 4

TAK-242 can alleviate collagen deposition in adhesive tissues (five groups; n = 8 mice/group). (A) Typical images of Sirius red staining, Masson staining and IHC staining of α-SMA in different groups. Magnification, x200, the area between the black arrows indicates adhesive tissue. (B) Fiber thickness in different groups as assessed by Sirius red staining. ^*P < 0.05, ^**P < 0.01 compared with the control group. (C) Fiber thickness in different groups as assessed by Masson staining. ^*P < 0.05, ^**P < 0.01 compared with the control group. (D) IHC staining scores of α-SMA in the different groups. ^*P < 0.05, ^**P < 0.01 compared with the control group