Table 2 Characteristics and SMN1 or SMN2 copy number groups in this study
From: SMN2 gene copy number affects the incidence and prognosis of motor neuron diseases in Japan
|  | Control (n = 399) | ALS (n = 487) | LMND (n = 50) | Control vs. ALS OR (95% CI) | Control vs. LMND OR (95% CI) |
|---|---|---|---|---|---|
Characteristics | |||||
Age (years) Mean (SD) | 62.2 (11.0) | 61.5 (11.1) | 58.4 (12.6) | - | - |
 M/F | 171/228 | 281/206 | 50/0 | - | - |
SMN1 copies | |||||
 1 copy | 5 (1.3%) | 4 (0.8%) | 0 (0%) | 0.65 (0.20–2.17) | - |
 2 copies | 364 (91.2%) | 457 (93.4%) | 47 (94.0%) | 1.46 (0.88–2.42) | 1.51 (0.46–4.82) |
 3 copies | 28 (7.0%) | 23 (4.7%) | 2 (4.0%) | 0.66 (0.37–1.13) | 0.55 (0.13–2.10) |
 4 copies | 2 (0.5%) | 3 (0.6%) | 1 (2.0%) | 1.23 (0.25–6.96) | 4.05 (0.27–35.2) |
SMN2 copies | |||||
 0 copy | 19 (4.8%) | 35 (7.2%) | 6 (12.0%) | 1.55 (0.88–2.75) | 2.73 (1.06–6.98)* |
 1 copy | 123 (30.8%) | 185 (38.0%) | 14 (28.0%) | 1.38 (1.04–1.81)* | 0.87 (0.46–1.68) |
 2 copies | 251 (62.9%) | 260 (53.4%) | 29 (58.0%) | 0.68 (0.52–0.89)* | 0.81 (0.45–1.47) |
 3 copies | 6 (1.5%) | 7 (1.4%) | 1 (2.0%) | 0.96 (0.35–2.87) | 1.34 (0.11–8.43) |