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Table 1 Demographics, clinical characteristics and treatment of critical patients with COVID-19

From: Fragmentomics of plasma mitochondrial and nuclear DNA inform prognosis in COVID-19 patients with critical symptoms

Characteristics

Alive group

Deceased group

P-value

n = 16

n = 17

ɑ = 0.05

 Age, years

65.8(56.8–72.8)

65.5(61–73)

0.9856

 Sex

  

0.1411

  Male

9(56.3%)

14(82.4%)

-

  Female

7(43.7%)

3(17.6%)

-

 ICU

2(12.5%)

16(94.1%)

< 0.0001

 Systolic pressure, mmHg

138.8(125–148)

132(120–146)

0.3043

 Oxygen therapy

16(100%)

17(100%)

-

 Mechanical ventilation

  Non-invasive

2(12.5%)

1(5.9%)

0.6012

  Invasive

1(6.3%)

13(76.5%)

< 0.0001

 ECMO

0 (0%)

1(5.9%)

1.0000

 CRRT

2(12.5%)

0 (0%)

0.2273

Underlying health conditions

 Hypertension

11(68.8%)

8(47.1%)

0.2960

 Type 2 diabetes mellitus

4(25%)

1(5.9%)

0.1748

 Chronic obstructive pulmonary disease

2(12.5%)

1(5.9%)

0.6012

 Cardiovascular disease

3(18.8%)

3(17.6%)

1.0000

 Cerebrovascular disease

3(18.8%)

2(11.8%)

0.6562

 Chronic kidney disease

1(6.3%)

2(11.8%)

1.0000

 Chronic liver disease

0 (0%)

2(11.8%)

0.4848

 Malignancy

0 (0%)

1(5.9%)

1.0000

Treatment

 Antiviral

14(87.5%)

17(100%)

0.2273

 Antibiotic

13(81.3%)

17(100%)

0.1026

 Antifungal

4(25%)

14(82.4%)

0.0016

 Glucocorticoids

10(62.5%)

17(100%)

0.0072

 Intravenous immunoglobulin therapy

6(37.5%)

15(88.2%)

0.0039

  1. Data are presented as mean (interquartile ranges, IQR) and no. (%)
  2. ICUintensive care unit, ECMO extracorporeal membrane oxygenation, CRRT continuous renal replacement therapy
  3. P-values comparing Alive group and Deceased group are from Fisher’s exact test or Kruskal–Wallis test, and P < 0.05 is considered statistically significant