Fig. 4

Discrimination of COVID-19 patients with different outcomes by using two- and three-dimensional features in cfDNA. A ROC plot for different combinations of features on the classification of alive and deceased patients. Scatter plots of two- and three-dimensional cfDNA characteristics for all alive or deceased patients with COVID-19, which are (B) accumulated deviation scores (ADS) and motif diversity score (MDS), C mitochondrial DNA size score (MSS) and MDS, (D) MSS and ADS, and E MSS, ADS and MDS. F Summary table of the performance for discrimination of COVID-19 patients with alive and deceased outcomes based on different combinations of cfDNA features