Table 10 Univariate and multivariate Logistic regression analysis for the parameters affecting COVID-19 severity and COVID-19 associated mortality (N = 140)

Male

0.39 (0.17–0.86)

0.02*

0.73 (0.25–2.17)

0.5

0.5(0.18–1.67)

0.3

Age

1.01 (0.97–1.04)

0.8

1.17 )1.08–1.28)

< 0.001*

1.18 (1.04–1.34)

0.01*

Low vitamin D

2.61 (1.16–6.18)

0.023*

3.61 (1.37–10.4)

0.01*

0.64 (0.41–0.99)

0.045*

High NLR

2.25 (1.01–5.08)

0.041*

1.19 (0.38–3.59)

0.8

1.05 (0.99–1.11)

0.08

High CRP

7.69 (3.06–22.3)

< 0.001*

5.80 (1.60–22.8)

0.009*

1.01 (1.0-1.02)

0.04*

High D-dimer

4.51 (1.98–10.7)

< 0.001*

1.05 (0.27–4.12)

> 0.9

1 (1-1.01)

0.7

High ferritin

2.75 (1.20–6.33)

0.017*

1.59 (0.54–4.71)

0.3

1 (1.00-1.1)

0.6

High LDH

4.55 (1.62–16.3)

0.008*

2.98 (0.83–13.2)

0.12

1 (0.99- 1)

0.3

Genotype (rs4588)

 CC (reference)

 AA

0.00 (00–00)

>0.9

0.00 (00–00)

0.9

 CA

1.08(0.44–2.54)

>0.9

1.08(0.44–2.54)

0.9

Genotype (rs7041)

 TT (reference)

 GG

1.65(0.50–6.5)

0.4

1.65(0.50–6.52)

0.4

 TG

1.60(0.49–6.2)

0.5

1.60(0.49–6.24)

0.5

Severity

4.61 (1.23–19.1)

0.025*

5.78(1.12–29.7)

0.03*

Diabetes

1.78 (0.58–5.42)

0.3

Hypertension

2.2 (0.71–6.62)

0.175

IHD

0

0.9

CKD

8 (1.93–33.1)

0.004*

0.827(0.08–8.4)

0.8

Chronic liver D

1.5 (0.32–7.93)

0.57

Medications

 Corticosteroids

0.34(0.07–2.49)

0.21

 Remdesivir

0.28(0.06–1.32)

0.12

 Actemra

0

> 0.9

 Anticoagulant

NA

0.9