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Fig. 4 | BMC Medical Genomics

Fig. 4

From: CLN3 transcript complexity revealed by long-read RNA sequencing analysis

Fig. 4

Summary of the top 15 CLN3 open reading frames (ORFs). The top 15 ORFs calculated by summing usage of all CLN3 transcripts containing specific ORFs are plotted in A; the canonical CLN3 ORF “CLN3_24_438aa” has a median usage of 66.7%, therefore around one-third of CLN3 transcripts encode different protein isoforms. The top 15 ORFs’ usage in different organs is plotted in B. The usage of the transcripts containing non-canonical ORFs is variable across organs

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