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Fig. 2 | BMC Medical Genomics

Fig. 2

From: Transcriptome-wide N6-methyladenosine modification profiling of long non-coding RNAs in patients with recurrent implantation failure

Fig. 2

Distribution of differentially methylated m6A sites. A The volcano plot indicates the distribution of differential m6A peaks the in RIF. Red and blue represent up- and downregulated peaks, respectively (fold-change ≥ 2.0, P < 0.00001 with Fisher’ s exact test). B The positional relationship between differentially m6A methylated lncRNAs and mRNAs. Orange, DodgerBlue, olive, light grey, blue and green represent exon sense-overlap, intergenic, intronic antisense, natural antisense, intron sense-overlap and bidirectional, respectively. C The distribution of altered m6A peaks per lncRNA. Blue and orange represent down- and upregulated peaks, respectively. D The chromosomal distribution of all differentially methylated sites within lncRNAs. Blue and orange represent down- and upregulated peaks, respectively

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