Table 1 Comparison of general physical parameters between the wild-type and mutant PPP1R12A proteins
From: Functional analysis of a novel nonsense PPP1R12A variant in a Chinese family with infantile epilepsy
Wild-type PPP1R12A | Mutant PPP1R12A (Arg845Ter) | |
|---|---|---|
Amino acids (N) | 1030 | 845 |
Molecular weight (Da) | 115280.71 | 93560.78 |
Isoelectric point (PI) | 5.31 | 5.35 |
Instability index | 61.87 | 64.30 |
Grand average of hydropathicity | 1.055 | 0.987 |
Aliphatic index | 62.08 | 62.04 |