Fig. 3
From: Functional analysis of a novel nonsense PPP1R12A variant in a Chinese family with infantile epilepsy
PPP1R12A protein model. (A) MD simulation of the PPP1R12A protein structure. RMSD data for wild-type and mutant proteins over 50 ns. (B) PPP1R12A protein model (aa 1–1030). (C) Mutant protein model showing the lack of folded and helical structures in the C-terminus of the truncated protein