Fig. 6

Assessment of immune status and immune cell infiltration patterns in BPD samples and control group samples. The immune score (A) and the stromal score (B) of DEGs in patients with bipolar disorder compared to healthy people based on the ESTIMATE algorithm. (C) Heatmap of 21 immune cell subpopulations in each BPD and control group sample. (D) Correlation heatmap of 21 immune cells. (E) Boxplot showing the differentially infiltrated immune cells between the two groups. (F) Correlation among four important ARDEGs and 21 differential immune cells. *p < 0.05, **p < 0.01, ***p < 0.001