Table 2 KEGG enrichment analysis of DEGs between control and aged groups

rno03010

Ribosome

5.58E-39

5.801469

Rps28; Rplp0; Rpl32; Rpl9; Rpl37a; Rpl38; Rpsa; Rpl41; Rpl19; Rps19; Rpl35a; Rps15a; Rpl36; Uba52; Rpl11; Rpl13; Rpl27a; Rpl26; Rpl34; Rps3; Rps24; Rpl30; Rpl23; Rpl14; Rps21; Rpl7a; Rps23; Rps8; Rpl17; Rpl37; Rpl28; Rps20; Rps18; Rps27a; Rpl12; Rps6; Rpl3; Rpl8; Rpl10a; Rps5; Rps4x; Rpl6; Rps27; Rplp2; Rpl29; Rpl36al; Rpl35; Rps7; Rpl18; Rpl22l1; Rpl18a; Rpl15; Rpl27; Rpl36a; Rpl5; Rps14; Rpl39; Rplp1; Rpl13a; Rps15; Rpl31; Rps11; Rpl7; Rps17; Rps29; Rps2; Rpl24; Rpl4; Rpl21; Rps12; Rps25; Rpl23a; Rps10; Rps27l; Rps16; Rpl10

rno04620

Toll-like receptor signaling pathway

0.000401

3.995148

Cxcl10; Irf7; Spp1; Ikbke; Fos; Ccl5; Map3k8; Cxcl9; Ccl4

rno05133

Pertussis

0.002322

3.811667

Rhoa; Irf1; Fos; Itgb2; C3; Nos2; Il10

rno05210

Colorectal cancer

0.002707

3.333819

Rhoa; Bcl2l11; Kras; Fos; Gadd45g; Ereg; Gadd45b; Ralgds

rno04623

Cytosolic DNA-sensing pathway

0.00282

4.224754

Zbp1; Cxcl10; Irf7; Ikbke; Ccl5; Ccl4

rno05206

MicroRNAs in cancer

0.004307

2.669234

Ezr; Marcks; Rhoa; Cd44; Zeb2; Bcl2l11; Kras; Socs1; Stmn1; Ptgs2

rno05140

Leishmaniasis

0.005798

2.943372

Ighg1; Fos; Ncf1; Itgb2; C3; Nos2; Il10; Ptgs2

rno05146

Amoebiasis

0.006731

2.663432

Gnas; Ighg1; Itgb2; Ctsg; Ighm; Nos2; Col3a1; Il10; Hspb1

rno05134

Legionellosis

0.009348

3.311293

Hspa8; Eef1g; Itgb2; Bnip3; C3; Eef1a1

rno04670

Leukocyte transendothelial migration

0.009608

2.700118

Ezr; Rhoa; Msn; Vasp; Rhoh; Rap1b; Ncf1; Itgb2

rno04210

Apoptosis

0.011812

2.43413

Bcl2l11; Kras; Fos; Cflar; Lmna; Gadd45g; Tuba1b; Gadd45b; Tuba1c

rno04062

Chemokine signaling pathway

0.014951

2.219526

Rhoa; Cxcl10; Kras; Rap1b; Ncf1; Ccl5; Fgr; Cxcl9; Hck; Ccl4

rno04668

TNF signaling pathway

0.017397

2.622706

Ifi47; Cxcl10; Fos; Cflar; Ccl5; Map3k8; Ptgs2

rno04611

Platelet activation

0.022393

2.317123

Rhoa; Vasp; Apbb1ip; Gnas; Rap1b; Ighm; Ppp1cb; Col3a1

rno04015

Rap1 signaling pathway

0.025129

1.961712

Rhoa; Vasp; Apbb1ip; Kras; Gnas; Rap1b; Itgb2; Fpr1; Prkd3; Ralgds; Flt1

rno04660

T cell receptor signaling pathway

0.026708

2.402311

Ptprc; Rhoa; Kras; Fos; Map3k8; Il10; Ctla4

rno05142

Chagas disease (American trypanosomiasis)

0.031235

2.324187

Gnas; Fos; Cflar; C3; Ccl5; Nos2; Il10

rno04657

IL-17 signaling pathway

0.035818

2.450357

Lcn2; Cxcl10; S100a9; Ikbke; Fos; Ptgs2

rno04917

Prolactin signaling pathway

0.038246

2.686795

Prl; Irf1; Kras; Socs1; Fos

rno05418

Fluid shear stress and atherosclerosis

0.038953

2.080983

Klf2; Rhoa; Nfe2l2; Mef2a; Fos; Sumo2; Ncf1; Sdc4