Fig. 5
From: Exploring novel MYH7 gene variants using in silico analyses in Korean patients with cardiomyopathy
DynaMut2 prediction of interatomic interactions of the native MYH7 vs. the variants. (a) Prediction scores of changes in protein stability using the DynaMut2 server. Interatomic interaction of MYH7 variants visualized using DynaMut2 in (b, c) p.Tyr134His and (d, e) p.Phe488Leu. Wild-type and mutant residues are indicated in a purple rectangle and represented as sticks along with the surrounding residues involved in the interaction. Dot points represent the interaction with the following color codes: pink, clash; light blue, VDW; red, hydrogen bond; yellow, ionic; light green, aromatic; green, hydrophobic; blue, carbonyl contacts