Fig. 7

The expressions of EGF, PLTP, RGS2, PTGDS in vivo and in vitro. HK-2 cells were treated with different concentration of glucose (5 mM, 20 mM, 30 mM) for 24 h, (A) mRNA expressions of EGF, PLTP, RGS2, PTGDS were detected. N = 3, **p < 0.01 vs. Vehicle, ***p < 0.001 vs. Vehicle. (B-C) Representative western blotting images (B) and quantifications (C) of EGF, PLTP, RGS2, PTGDS were showed. N = 3, *p < 0.05 vs. Vehicle, **p < 0.01 vs. Vehicle, ***p < 0.001 vs. Vehicle. (D) mRNA expressions of EGF, PLTP, RGS2, PTGDS were detected in the kidney tissues of mice with DN or the control mice. N = 6 per group, ***p < 0.001 vs. Ctrl