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Table 4 Logistic regression analysis to predict the risk of knee OA

From: Serum lncRNA ITGB2-AS1 and ICAM-1 as novel biomarkers for rheumatoid arthritis and osteoarthritis diagnosis

Parameter

β-coefficient

SE

P-value

OR

95% CI

Univariate analysis

ITGB2 mRNA

1.05

0.529

0.047

2.859

1.014–8.062

ICAM-1

0.008

0.0028

0.003

1.008

1.003–1.014

Multivariate analysisa

ITGB2 mRNA

0.112

0.475

0.814

1.118

0.44–2.84

ICAM-1

0.009

0.0035

0.0096

1.009

1.002–1.016

Constant

− 4.73

    
  1. Chi-square of the best multivariate logistic regression model = 55.74, P = 0.00, adjusted by age and sex as covariates using data of knee OA patients (n = 35) and healthy controls (n = 22). Bold indicates statistical significance, P < 0.05.a adjusted for age and sex in the multivariate analysis. CI, confidence interval; ICAM-1, intercellular adhesion molecule-1; ITGB2; integrin beta 2 subunit; OR, odds ratio; SE, standard error
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BMC Medical Genomics

ISSN: 1755-8794

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