Leisure television watching exerts a causal effect on gastroesophageal reflux disease: evidence from a two-step mendelian randomization study

Table 1 Mediation effect of television watching on GERD via mediators

Exposure	Mediator	Outcome	Total effect^a	Effect A^b	Effect B^c	Mediation effect^d		Mediated proportion
Exposure	Mediator	Outcome	β (95% CI)	β (95% CI)	β (95% CI)	β (95% CI)	P	(%)	(95% CI)
Television watching	Cigarettes smoked per day	GERD	0.29 (0.13–0.44)	0.32 (0.23–0.41)	0.17 (0.06–0.27)	0.05 (0.02–0.09)	0.0038797	18.37%	11.94–39.79

^a Total effect, the effect of per 1-SD increase in leisure time television watching on GERD; ^b Effect A, the effect of per 1-SD increase in leisure time television watching on mediators; ^c Effect B, the effect of per 1-SD increase in the mean value of mediators on GERD; ^d Mediation effect, the indirect effect of per 1-SD increase in leisure time television watching on GERD via mediators

ISSN: 1755-8794