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Table 1 Clinical and biological characteristics of the subjects

From: Major depletion of insulin sensitivity-associated taxa in the gut microbiome of persons living with HIV controlled by antiretroviral drugs

 

PWH vs. Microobes

PWH vs. Metahit

PWH vs. Metacardis

PWH N=25

Microobes N=25

p. overall

PWH N=25

Metahit N=25

p. overall

PWH N=25

Metacardis N=25

p. overall

BMI (kg/m2)

25.0 (4.2)

32.7 (3.7)

8.7e-07

25.0 (4.2)

26.0 (4.4)

0.64

25.0 (4.2)

23.2 (1.58)

0.071

Waist circumference (cm)

97.9 (6.2)

105 (9.2)

0.024

97.9 (6.2)

. (.)

.

97.9 (6.2)

83.1 (7.17)

1.1e-05

Hip circumference (cm)

98.7 (3.6)

114 (9.3)

5.3e-06

98.7 (3.6)

. (.)

.

98.7 (3.6)

96.3 (5.2)

0.24

CRPus (mg/L)

5.9 (10.4)

5.3 (6.9)

0.23

5.9 (10.4)

. (.)

.

5.9 (10.4)

1.5 (1.7)

0.082

INS (µU/ml)

19.2 (20.1)

8.11 (3.7)

0.0031

19.2 (20.1)

. (.)

.

19.2 (20.1)

5.23 (3.35)

2.2e-06

LDL-cholesterol (mmol/L)

2.83 (0.92)

3.30 (0.75)

0.066

2.83 (0.92)

. (.)

.

2.83 (0.92)

2.82 (0.70)

0.77

HDL-cholesterol (mmol/L)

1.22 (0.32)

1.41 (0.36)

0.037

1.22 (0.32)

. (.)

.

1.22 (0.32)

1.66 (0.43)

0.00036

SBP (mm Hg)

138 (22.6)

119 (13.0)

0.026

138 (22.6)

. (.)

.

138 (22.6)

123 (15.8)

0.074

Glycemia (mmol/L)

5.79 (1.02)

5.31 (0.46)

0.14

5.79 (1.02)

. (.)

.

5.79 (1.02)

4.92 (0.52)

0.00031

IL-6 (pg/mL)

3.73 (5.72)

2.17 (1.72)

0.99

3.73 (5.72)

. (.)

.

3.73 (5.72)

1.67 (1.05)

0.62

sCD14 (ng/mL)

1595 (226)

1382 (390)

0.009

1595 (226)

. (.)

.

1595 (226)

1470 (305)

0.039

Adiponectin (µg/mL)

3.30 (2.04)

14.1 (6.93)

1.3e-07

3.30 (2.04)

. (.)

.

3.30 (2.04)

6.28 (4.18)

0.0027

HOMA-IR

5.12 (5.03)

1.93 (0.91)

0.00081

5.12 (5.03)

. (.)

.

5.12 (5.03)

1.16 (0.73)

1.7e-06

Gender:

  

0.00023

  

0.7

  

1

   Female

5 (20.0%)

19 (76.0%)

 

5 (20.0%)

3 (12.0%)

 

5 (20.0%)

5 (20.0%)

 

   Male

20 (80.0%)

6 (24.0%)

 

20 (80.0%)

22 (88.0%)

 

20 (80.0%)

20 (80.0%)

 

Age (years)

53.1 (7.0)

47.9 (10.3)

0.14

53.1 (7.0)

52.7 (8.2)

0.83

53.1 (7.0)

53.2 (12.5)

0.55

  1. Results are given as mean (SD). Pairwise differences in clinical variables between PWH and each of the control groups were evaluated by Wicoxon rank-sum test (continuous variables) and Chi-square tests (categorical variables). BMI: body mass index; INS: fasting insulinemia; SBP: systolic blood pressure; sCD14: soluble CD14
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BMC Medical Genomics

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