Fig. 5

Composition of Predomics Family of Best Models (FBM) in PWH classification vs. control groups. (A) Summary plot of the feature presence/absence (left panel), mean feature importance (center panel) and feature prevalence across study groups (right panel) for the 39 MGS (y-axis) retained in 718 bininter models included in the FBM in each prediction task (PWH vs. different control groups; n = 511 models in PWH vs. MetaCardis, 132 models in PWH vs. Metahit; 75 models in PWH vs. MicroObes). (B) Same as panel B for the 37 MGS retained in 669 terinter models included in the FBM in each prediction task (PWH vs. different control groups; n = 14 models in PWH vs. MetaCardis, 155 models in PWH vs. Metahit; 500 models in PWH vs. MicroObes). Blue and red MGS in model presence/absence and feature importance panels represent MGS with high mean abundances in control or PWH groups respectively. Core facet corresponds to MGS retained at least once in the FBM of each prediction task