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Fig. 2 | BMC Medical Genomics

Fig. 2

From: Major depletion of insulin sensitivity-associated taxa in the gut microbiome of persons living with HIV controlled by antiretroviral drugs

Fig. 2

Differentially abundant metagenomic species (MGS) across study groups. (A) Heatmap of Cliff’s Delta effect sizes (left panel) of 121 MGS with significant differences in abundance between HIV individuals (n = 25) and MicroObes (n = 25), MetaHit (n = 25) or MetaCardis (n = 25) individuals (#=FDR < 0.05; *=p-value < 0.05; Wilcoxon rank-sum test). Positive values correspond to MGS significantly increased in the PWH group, whereas negative values correspond to MGS significantly depleted in the PWH group. Right panel represents the robustness of the associations to MSM status (FDR < 0.1; Wilcoxon rank-sum test in MSM vs. control and no-MSM vs. control comparisons; n = 13 MSM, n = 10 no-MSM). (B-E) Boxplots of log-transformed MGS abundances across study groups for the 4 MGS highlighted in green in panel A

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BMC Medical Genomics

ISSN: 1755-8794

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