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Table 3 Genetic model analyses of the candidate SNPs in VSD and normal populations

From: FLT4 gene polymorphisms influence isolated ventricular septal defect predisposition in a Southwest China population

Gene (SNP)

Genotype

VSD Freq

Control Freq

P value

OR (95% CI)

FLT4(rs383985)

     

Dominant

MM + MW

0.34

0.43

0.029

0.69(0.50–0.90)

 

WW

0.66

0.57

  

Recessive

MM

0.04

0.05

0.531

 
 

MW + WW

0.96

0.95

  

Additive

MM vs. MW vs. WW

0.04 vs. 0.30 vs. 0.66

0.05vs. 0.38vs. 0.57

0.355

 
  1. P value in boldface indicates statistical significance (P < 0.05). SNP, single nucleotide polymorphism; Freq, frequency; OR, odds ratio; CI, confidence interval