Table 3 KEGG pathway analysis of six hub DEmRNAs
KEGG Pathway | P-value | Enrichment | HitGenes |
|---|---|---|---|
HIF-1 signaling pathway | 3.35E-12 | 230.75 | HIF1A, IGF1R, PIK3R1,MAP2K1,VEGFA |
Focal adhesion | 7.44E-11 | 125.13 | CDC42,IGF1R, PIK3R1,MAP2K1,VEGFA |
Rap1 signaling pathway | 9.28E-11 | 119.77 | CDC42,IGF1R, PIK3R1,MAP2K1,VEGFA |
Ras signaling pathway | 1.67E-10 | 106.57 | CDC42,IGF1R, PIK3R1,MAP2K1,VEGFA |
VEGF signaling pathway | 1.97E-10 | 341.04 | CDC42,PIK3R1,MAP2K1,VEGFA |
Autophagy - animal | 6.8E-09 | 142.70 | HIF1A, IGF1R, PIK3R1,MAP2K1 |
MAPK signaling pathway | 1.3E-07 | 68.44 | CDC42,IGF1R, MAP2K1,VEGFA |
PI3K-Akt signaling pathway | 2.74E-07 | 56.84 | IGF1R, PIK3R1,MAP2K1,VEGFA |
T cell receptor signaling pathway | 7.89E-07 | 145.11 | CDC42,PIK3R1,MAP2K1 |
FoxO signaling pathway | 1.58E-06 | 115.20 | IGF1R, PIK3R1,MAP2K1 |
mTOR signaling pathway | 2.68E-06 | 96.74 | IGF1R, PIK3R1,MAP2K1 |