Table 1 Overview of the four genome-wide association studies (GWAS) used in this study. GWAS ID is the identifier in the GWAS catalogue. The number of independent loci was determined using the Downstreamer methodology (see Methods). Number of cases is the number of European ancestry cases reported by the GWAS catalogue
Study | GWAS ID | Cancer | Number of independent loci | Number of cases |
|---|---|---|---|---|
Schumacher et al., Nat. Genet. 2018 | GCST006085 | Prostate | 335 | 79,148 |
Zhang et al., Nat. Genet. 2020 | GCST010098 | Breast | 348 | 133,384 |
Sakaue et al., Nat. Genet. 2021 | GCST90018921 | Skin | 123 | 25,928 |
Fernandez-Rozadilla et al., Nat. Genet. 2022 | GCST90102485 | Colorectal | 99 | 100,204 |