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Fig. 2 | BMC Medical Genomics

Fig. 2

From: Co-expression in tissue-specific gene networks links genes in cancer-susceptibility loci to known somatic driver genes

Fig. 2

Enrichment of cancer-specific somatic driver genes for different multi-tissue and tissue-specific gene-prioritisation methods applied to cancer GWAS summary statistics. A one-sided Wilcoxon rank-sum test was used to calculate the enrichment of cancer-specific driver genes in the list of prioritised genes (x-axis) for four cancer GWAS studies (y-axis). Open diamonds indicate gene enrichment values for the original GWAS, calculated with PascalX from the GWAS summary statistics. Coloured symbols indicate the enrichments for the different tissue networks, calculated using Downstreamer

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BMC Medical Genomics

ISSN: 1755-8794

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