Fig. 2

Identification of differentially expressed lncRNAs in condyloma acuminatum. (a-b) Venn diagram showing the number of detected lncRNAs. The known and new predicted lncRNAs were detected (expressed in at least 1 sample with FPKM > 0). (c-f) PCA based on the FPKM value of all mRNAs, all lncRNAs, differentially expressed mRNAs and differentially expressed lncRNAs. The ellipse for each group is the confidence ellipse. (g-h) Volcano plot showing differentially expressed mRNAs and lncRNAs between the CA group and the CON group, with cut-offs of DEseq2. FDR < 0.05 and FC ≥ 2 or ≤ 0.5. (i) Heatmap showing the expression profile of the top 15 significantly upregulated and downregulated lncRNAs