Table 8 Distribution of high variation frequency sites in Han nationality
Variation sites | Control groups | Case groups | P values | Amino acid changes | ||
|---|---|---|---|---|---|---|
Number of variation samples(n = 31) | Variation frequency | Number of variation samples(n = 21) | Variation frequency | |||
T2520C | 11 | 35.48% | 8 | 38.10% | 0.848 | L18L |
C2546T | 26 | 83.87% | 19 | 90.48% | 0.494 | T26T |
G2585A | 9 | 29.03% | 9 | 42.86% | 0.304 | P39P |
A3115Ca | 19 | 61.29% | 19 | 90.48% | 0.02 | I44La |
C3127A | 4 | 12.90% | 1 | 4.76% | 0.329 | L48I |
C3127G | 1 | 3.23% | 2 | 9.52% | 0.339 | L48V |
G3622A | 3 | 9.68% | 6 | 28.57% | 0.77 | D84N |
G3641A | 10 | 32.26% | 10 | 47.62% | 0.264 | R90K |
G3658A | 11 | 35.48% | 11 | 52.38% | 0.226 | D96N |
T4177C | 13 | 41.94% | 11 | 52.38% | 0.458 | S269P |
A4362C | 21 | 67.74% | 11 | 52.38% | 0.264 | L330F |
A4362T | 7 | 22.58% | 7 | 33.33% | 0.391 | L330F |
A4654C | 8 | 25.81% | 8 | 38.10% | 0.346 | I428L |